I've got this exact board, and having configured it properly now I've got quite a solid system working..
Audio, Graphics, Sleep, Power Management, most USB ports are all working. The only thing that isn't is Thunderbolt 3 (to be expected because there's yet to be an Apple system with such functionality).
I run a GTX 970; I haven't tried using the iGPU (also an HD 530) with that concurrently, to be honest that sounds like a recipe for trouble. Keep it simple and stick to one or the other. Just install the Nvidia drivers and set the appropriate flag on boot through Clover Configurator.