I've been following the DRM thing on a few different threads and sites. It looks like those running Vega and newer are not having the issue. Those that are running Polaris RX 4xx-5xx cards seem to be most affected. DRM works in most places (sometimes requiring weg boot arguments) but you can get TV app, iTunes working. The problem is with DRM in Safari with sites like Netflix/Prime, and it looks like the WEG team is aware of it and working on it.
If I'm on iMacPro1,1 SMBIOS, the machine will completely lock up when trying to visit these sites in safari. On iMac19,1 headless, the site will give an error but not lock up the machine.