Not for me on Z170X-UD5-TH/HD530 graphics
Nuts! I was hoping we'd have a universal (motherboard wise) fix for this problem. So, far only one ASUS system worked.Same-
Updated to clover 3556, changed bios ErP and have shutdownfix + SlpSmiAtWake options in clover and it did not fix it for me, but again it might be my watercooling usb.
I would try to use the latest Multibeast to just reinstall the drivers for Skylake/1150 audio. I ran MB twice as per the instructions (with an older version of MB)