Just this past couple of days I tried to get it working and getting to a usable state (I still have slow and flicker and sometimes no second monitor) could not.
Something interesting though, my system did not recognize the Graphics card, but if I booted into safe mode, The card was recognized and so was both monitors.
So Wonder if has something to do with NVIDIA Web Drivers? I am right now doing a clean reinstall of Sierra. Contemplating doing a High Sierra install (No Web Drivers installed) to see what happens? Though if I cannot get acceleration enabled not sure what the point will be.