I don't know that DVI is a good thing. If you can test with just straight HDMI that would be best.
As for the sysdef, 18,3 would be the wrong one, you'd want n,1 as that, if I am not mistaken, does not spec discrete gpu (uses the chip's onboard graphics).
Make a copy of your current config file (use a meaningful name) before changing your sysdef. That way you can revert w/o issue.
Yes, changing sysdefs will temporarily disrupt your iStuff as you are changing "computers." So you will need to re-do the iStuff.
Alternatively, if you want to keep the 18,3, you'll need a GPU - either AMD or NVidia. If NVidia, I'd recommend no less than the 1070. With AMD either the 580 or Vega 56.