I have the Gigabyte GA-Z170-HD3 DDR3 Motherboard with an i5-6400 under 10.11.5, all my USB ports work, Ethernet works, the HD 530 graphics work, BUT IT WILL NOT WAKE THE SCREEN FROM SLEEP! I had to fit an NVidia card to achieve that, (GE Geforce 740 + NVidia web drivers and the boot argument to switch on NVidia drivers in config.plist). This board actually shuts down properly (no spinning permanent fans) but I cannot get the ALC887 Codec to work from Multibeast. Other people with another version of this board (minus the DDR3) seem to have no problems getting the Codec working but I think I will have to get a USB sound card. I think it's a great value board, simply because barring the sound, it takes to EL Capitan very well which is worth the money. There may be cheaper boards with the same chipsets, but that was a risk I wasn't prepared to take and it seems to have paid off.