Audioguyjosh, thank you for your write up! This helped me pull the trigger on building a similar system for Pro Tools. I've tested Mavericks, Yosemite, El Cap, and Sierra and Mavericks and Sierra seem to work the best. Yosemite and El Cap just don't want to restart or shutdown properly regardless of EveOreboot kext or any Clover fixes. I had no idea previously you could build a system of this level for so cheap on eBay
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CPU: 2x X5650 6 core 2.6GHz
Mobo: X8DTL-i
Ram: Hynix 4x 4GB 1333MHz ECC Registered (HMT351R7BFR8C-H9)
GPU: EVGA GTX 650 (no NVIDIA driver)
PSU: EVGA 650BQ
SSD: 830 and 840 Pro
WIFI: TP Link N900
AUDIO: Focusrite 2i2 USB audio interface
SMBIOS Mac Pro 5,1 (this processor was used in 2010 Mac Pro 5,1 Westmere)
I used UniBeast 7 and MB 9 for Installation with Tonymac Sierra guide.
Problems with Sierra:
-System only seeing 8 out of 16GB I had installed, which I fixed by manually typing in the ram specs into SMBIOS on Clover Configurator.
-GTX 650 reading 0GB of VRAM. Tried installing NVIDIA driver, but stopped with the problem of the OS switching back to OS X driver after restart. Tried installing EmuVariableUefi-64, but no luck. Not sure I want to install RC Script using the Clover custom installer because it also wants to install Drivers64UEFI and who know what can of worms that will be.
Link for fix (Problem6):
https://www.tonymacx86.com/threads/solving-nvidia-driver-install-loading-problems.161256/
EDIT: Turned off Inject NVIDIA in Clover and system now reads correct VRAM
-Sleep does not work and I haven't tried fixing it, not sure if there is one.
Haven't tested Ethernet
Don't have anything to test USB3 with.
Didn't Bother with iMessage and I only use USB audio
Pro Tools 12.5.2 appears to be working just fine with Sierra, but I haven't spent much time with it, don't have access to 12.6.
That's my story if it helps anyone.