Just a quick update to this....
It eventually stopped working on me, again.
But hadn't had much time to deal with it. And then while working to repair my iMessage (which I am still doing), I was reading the how to fix iMessage thread and it suggested to change your Mac profile to an iMac 14,2 which works better with the Haswell chipset..... once I did that...DONE!.
Sound has not been an issue after starting up the system from sleep mode.
Even issues with keyboard response when I was typing on my wireless keyboard and using the mouse, have almost gone away.
So give it a try if you guys have not done so, and see how it goes.
Thanks for the help.