You can use AMD cards on LGA 775 motherboards on MacOS Mojave and Catalina. You just need kexts for SSE 4.2 emulation for CPUs that do not support it. Check these posts 1 and 2. You can also check this post about telemetrap.kext which supposedly prevent com.apple.telemetry.plugin from executing. So everytime you make updates or fresh install you don't have delete or replace com.apple.telemetry.plugin.I remember a lot of the old school stuff, but with the AMD graphics cards on older systems I don’t think that there’s a fix. Set up my first Hackintosh in 2010. A lot has changed.