I have the same configuration as you have.
My motherboard is
Z68xp ud3. Bios Version is 8. ( not UEFI ) Legacy
Amd Radeon 6870
Intel I7 2600K
My system works fine and boots normally. First I got stuck at the boot process until I disabled USB 3 in BIOS.
Strange thing is that my friend has the the same system as I do except the Graphics card , he has Amd Radeon 6850. It boots fine with the USB drive, everything works normal BUT When booting from his Sierra install hard disk the clover boot screen is garbled ( like 8 bit graphics ) then when it finish starting up it only show like a 1/6th of the whole screen.
The most strange thing is that I took the graphics card from my computer and installed in his, but still the same , We compared everything btw mine and his computer, even the bios and every line in the config. plist. Now we are thinking of trying a new PSU in his computer just to see if it changes anything.
If that don't work then we are gonna make a Sierra installer on a SSD and just run it from there , should work the same as starting from the USB Drive , just much faster.