When you say you're using his settings, are you using the ASUS MultiCore Enhancement to "Auto", AVX Instruction Core Ratio Negative Offset to "3", AVX-512 Instruction Core Ratio Negative Offset to "2", and CPU Core Ratio to "Sync All Cores"? I didn't use those settings - I used the "optional" settings (Disabled, Auto, Auto, Auto) because it seemed like my Water cooler (similar one to yours - mine is the Corsair H100i v2) might not be strong enough.
I did put the IOCPUNumber to 27 in the TSCAdjustReset.kext.