usb driver

I update my System with High Sierra to Mojave. I can boot and anything is ok. But after maybe 20-40sec no USB-Port works anymore. Sometimes, (maybe) every third time the USB doesn't stop working. I don't know what to do. Thanks for helping.

Can't find Lenovo z500 usb driver,can not use USB harddisk,please help? OS X 10.9.1