My config : gigabyte Z270N-Wifi, i5, RAM 16 gig. No graphics cards. Bios OK : VT-D disabled, other Os, DVMT 64...
No problem with installation, have run Multibeast with the following options : UEFI Boot Mode, ALC 1220 and 100/200 Series audio, IntelMausiEthernet 2.2.d1, increase max port 200...