I know this is an old thread but I thought I would let everyone know that I have High Sierra up and running on a x150M PRO ECC (F1 Bios) board and a Xeon E3 1230 V5, 32 GB ECC (Kingston 4x8GB, 2133), Nvidia/EVGA 1060 3GB, and Samsung 970 EVO NVMe drive. Everything is working nicely except my raid drives don't show up (I have two sets, one RAID 1 and one RAID 0), and drives plugged into some USB ports don't seem to show up either. Two monitors are up and running and I have audio running through a FX-Audio D802 amp through usb for some killer sound. I have Mojave downloaded but am a little hesitant to break anything as I just got it working adequately. Any suggestions on the usb and raid issues?