Awesome thread!
I got this board running with Mojave a couple days ago by using a copy of an EFI folder that I compiled for a z390 Designare build. Luckily, I stumbled across this thread when attempting to find out why the USB 3.1 Type-C port wasn't working (all was well when using the internal header of my previous Designare build).
Thank you
@jbarnette for providing the custom SSDT; however - after initial tests it appears that the pair of USB 3.0 ports next to the PS/2s seem to be working at full speed with USB 3.0 devices! But like you, my internal USB 2.0 header now no longer works (FWIW I did a recent build of this running High Sierra and all the USB ports are functional, but no biggie either way
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Oh yeah, I must also note that I'm using a 9900KF, which doesn't have integrated graphics, so I'm thinking I might be better served going with an iMac Pro System Definition?
Lastly, I attached my EFI for reference.
9900KF
Z390 M Gaming
Sapphire 11266-06-20G Radeon Pulse RX 570 ITX 4GB
16GB Crucial Ballistix Sport LT 2400 MHz DDR4 DRAM (upgrade to 32GB shortly)
Gigabyte Alpine Ridge Thunderbolt 3 card
Fenvi FV-T919 Wireless AC1300 PCI Express Wi-Fi Adapter
Hopefully this helps!