Update to 10.8.4 done flawlessly on MAXIMUS IV GENE-Z - i7 2600K - GeForce GTX 560 Ti
I had to re-apply MultiBeast 5.3.1 for Realtek ALC889 driver. Just to be sure, also re-apply USB3, and other fancy stuff...
[Edit] Also, I had to re-apply Freezefix for my 560Ti.
Used combo update and reapplied ALC889 driver before reboot. Since I have an i5 2400, I also had to revert AppleACPIPlatform.kext to an earlier hacked version, using KextBeast. Rebooted and everything's super.