Hi, EddyMac,
Just to put my 2 cents into the fray, I use the Targus BT USB dongle (see my build description for model) w/o any lag, and my Magic Mouse wakes up my hacks. I have the Targus plugged into the front USB port of my IOGear KVM switch; all computers use it when I switch to different systems almost instantly. My Logitech Unifying Receiver for the K750 Solar Mac KB is plugged into the monitor. So, I've have my BT & Unifying Receiver in USB hubs. But, you need to sacrifice a chicken each day for it to work which they don't tell you in the manual.
I have bad eyes so I, too, use 23/24" IPS monitors giving me 1920x1200 resolution which are soooo much better than the cheapo TFN 1080p resolution monitors. The HP ZR24W/ZR2440W monitors are priced reasonably. I have a ZR24W and an Apple 23" ACD (DVI) monitors which are good for my eyes.
One of my systems uses a Fractal Design Define R3 (R4 is the current model) case. Outstanding case! Highly recommended. I'm now looking to get a Fractal DD Mini for my mATX based computers.