I have just upgraded my Hp 250 G6 from 10.13.2 to 10.13.3 and the only issue I can see is the brightness slider is now missing. I had used the clover patch for the backlight in 10.13.2, and had patched DSDT for the brightness keys. So this looks like the patch for the backlight kext may now need changing?
Edit: The backlight is now working. Looks like I just needed to refresh the cache. So the 10.13.3 update for the hp 250 g6 went perfectly. Everything working sleep/wake, Power management, Card reader, Audio, HDMI, trim, brightness, iMessage etc. I haven't noticed any performance degradation as yet. So in all, everything working on this notebook except the stock intel wifi, which I will change out for a compatible one soon. The USB TP-link TL-WN725N wifi is working fine in the meantime.