Dude... you now do not have any TSCAdjustReset.kext in your EFI-Folder.
Once a properly adapted TSCAdjustReset.kext is back in your EFI-Folder, your Designare EX system should boot now with your current EFI-Folder configuration.
Anyway, at first place try to boot with one Nvidia GPU only.
Revise your BIOS settings in case the boot problem still remains. Also try to enable/disable "above 4G decoding".
I do not have any save of SSDTs I might have created for the Designare EX once. You can only investigate both X299 threads, if I attached such SSDTs once.
There are also no XHC USB kexts for the Designare EX yet available in the respective Github library, as no Designare EX user was providing or willing in helping to provide the latter. Thus you will have to come up with new Designare EX XHC USB kexts in any case.
Last but not least, TB HotPlug will also not work with the onboard Alpine Ridge controller of the Designare EX, thus I really don't know what for all these efforts..
You do not want to directly switch to the ASUS WS X299 Sage 10G + GC-Titan Ridge controller?
Well I don't want to spend again my entire day here in this forum and I have to arrange several things in real life for now. Thus, I just hope that you take the correct decision how to proceed with your endeavours in line with your personal skills. In any case, for the ASUS WS X299 Sage 10G + GC-Titan Ridge controller you would have SSDTs and XHC USB kexts already available and also TTR TB would work including TB and USB-C HotPlug and sleep/wake as well as the two onboard 10GB NICs would be fully functional after following my respective guidelines.
As you already returned the Deluxe II and in case you would also sell your Designare EX, the resulting budget should be more than sufficient to go for the ASUS WS X299 Sage 10G + GC-Titan Ridge controller solution, where also
@djlild7hina can provide help and support.