USBWakeFixup just helps the system wake with one mouse click. Without it, I needed 2-3 mouse clicks before the system would fully wake. It's not meant to fix any kernel panics.
What do your kernel panics say?
Try running without WhateverGreen and see if you still get kernel panics.
I sold my Radeon VII a few weeks ago, but I never had any major issue with it. My system was extremely stable. However, I never tried running macOS on any resolution other than the native 4K and I don't even have Chrome installed.
Maybe I spoke too soon, I was using remote desktop, the mouse started to lag, and a few seconds later Kernel panic.
Panic(CPU 0, time 4863941625795): NMIPI for spinlock acquisition timeout, spinlock: 0xffffff870fdd9e00, spinlock owner: 0xffffff8705cb7d10, current_thread: 0xffffff8705cb7d10, spinlock_owner_cpu: 0x0
RAX: 0x0000000000000000, RBX: 0x0000000000000004, RCX: 0xffffff80002d2323, RDX: 0xffffff80002d262c
RSP: 0xffffffa10629be00, RBP: 0xffffffa10629be80, RSI: 0x0000000000000004, RDI: 0xffffffa17c7f5024
R8: 0x0000000000000000, R9: 0x0000000000000024, R10: 0x0000000000000001, R11: 0x0000000000000000
R12: 0x0000000000000000, R13: 0x0000000000000000, R14: 0x0000000080000001, R15: 0xffffffa17c7f5024
RFL: 0x0000000000000093, RIP: 0xffffff80002d2326, CS: 0x0000000000000008, SS: 0x0000000000000000
Backtrace (CPU 0), Frame : Return Address
0xffffffa10629bcb0 : 0xffffff80003ed5bb mach_kernel : _interrupt + 0x12b
0xffffffa10629bd00 : 0xffffff800025fd39 mach_kernel : _return_to_iret + 0x159
0xffffffa10629be80 : 0xffffff7f9f135692 com.apple.driver.AppleGFXHDA : __ZN21AppleGFXHDAController15interruptFilterEP28IOFilterInterruptEventSource + 0xfa
0xffffffa10629bed0 : 0xffffff8000a1bd91 mach_kernel : __ZN28IOFilterInterruptEventSource23normalInterruptOccurredEPvP9IOServicei + 0x81
0xffffffa10629bf00 : 0xffffff8002c40beb com.apple.iokit.IOPCIFamily : __ZN32IOPCIMessagedInterruptController15handleInterruptEPvP9IOServicei + 0x12b
0xffffffa10629bf50 : 0xffffff8001299510 com.apple.driver.AppleACPIPlatform : __ZN23AppleACPIPlatformExpert23dispatchGlobalInterruptEi + 0x2e
0xffffffa10629bf60 : 0xffffff80012a224f com.apple.driver.AppleACPIPlatform : __ZN31AppleACPICPUInterruptController15handleInterruptEPvP9IOServicei + 0x6b
0xffffffa10629bf80 : 0xffffff80003ed60d mach_kernel : _interrupt + 0x17d
0xffffffa10629bfd0 : 0xffffff800025fbdd mach_kernel : _hndl_allintrs + 0x11d
0xffffffc181a83d60 : 0xffffff80007f54ed mach_kernel : _workq_thread_set_max_qos + 0x66d
0xffffffc181a83dc0 : 0xffffff80007f9b3d mach_kernel : _workq_kern_threadreq_initiate + 0x2ed
0xffffffc181a83e10 : 0xffffff800082300e mach_kernel : _kevt_getstat + 0x1d1e
0xffffffc181a83e50 : 0xffffff8000824014 mach_kernel : _kqueue_alloc_turnstile + 0xfb4
0xffffffc181a83e80 : 0xffffff80002ff725 mach_kernel : _thread_call_delayed_timer + 0x4a5
0xffffffc181a83ef0 : 0xffffff8000300634 mach_kernel : _thread_call_delayed_timer + 0x13b4
0xffffffc181a83fa0 : 0xffffff800025f13e mach_kernel : _call_continuation + 0x2e
Kernel Extensions in backtrace:
com.apple.iokit.IOPCIFamily(2.9)[BF2C5E86-1E8F-3FD4-9874-7738178FA73B]@0xffffff8002c1f000->0xffffff8002c46fff
com.apple.driver.AppleACPIPlatform(6.1)[2F2AA264-6BD5-3E4F-829C-8952B3ABB2D5]@0xffffff8001292000->0xffffff8001308fff
dependency: com.apple.driver.AppleSMC(3.1.9)[1E48B8EB-7BF3-3366-8520-2C4B31A7D3F8]@0xffffff8001895000->0xffffff80018adfff
dependency: com.apple.iokit.IOACPIFamily(1.4)[B41AA072-8BB9-3493-9796-6FF849CDABB8]@0xffffff80026d8000->0xffffff80026d9fff
dependency: com.apple.iokit.IOPCIFamily(2.9)[BF2C5E86-1E8F-3FD4-9874-7738178FA73B]@0xffffff8002c1f000->0xffffff8002c46fff
com.apple.driver.AppleGFXHDA(100.1.431)[71E02A6A-3166-397B-B393-85C77BDCC615]@0xffffff7f9f12d000->0xffffff7f9f18afff
dependency: com.apple.iokit.IOAudioFamily(300.6.1)[8CBD98F6-7011-35DA-B0A7-47EF6636B572]@0xffffff800273b000->0xffffff8002758fff
dependency: com.apple.iokit.IOGraphicsFamily(585)[EF8876FC-C6D6-3D53-9915-762EF4F12870]@0xffffff7fa0a63000->0xffffff7fa0a91fff
dependency: com.apple.iokit.IONDRVSupport(585)[40BEBEA2-BBB5-3B09-B6AE-B4B372775FBD]@0xffffff7fa0aa8000->0xffffff7fa0ab0fff
dependency: com.apple.iokit.IOPCIFamily(2.9)[BF2C5E86-1E8F-3FD4-9874-7738178FA73B]@0xffffff8002c1f000->0xffffff8002c46fff
Process name corresponding to current thread: kernel_task
Boot args: -v -alcbeta -lilubetaall debug=0x100 keepsyms=1 -wegbeta -vsmcbeta darkwake=10
Mac OS version:
20D91
Kernel version:
Darwin Kernel Version 20.3.0: Thu Jan 21 00:07:06 PST 2021; root:xnu-7195.81.3~1/RELEASE_X86_64
Kernel UUID: C86236B2-4976-3542-80CA-74A6B8B4BA03
KernelCache slide: 0x0000000000000000
KernelCache base: 0xffffff8000200000
Kernel slide: 0x0000000000010000
Kernel text base: 0xffffff8000210000
__HIB text base: 0xffffff8000100000
System model name: iMacPro1,1 (Mac-7BA5B2D9E42DDD94)
System shutdown begun: NO
Panic diags file available: YES (0x0)
Hibernation exit count: 0
System uptime in nanoseconds: 4863941949740
Last Sleep: absolute base_tsc base_nano
Uptime : 0x0000046c79883add
Sleep : 0x0000000000000000 0x0000000000000000 0x0000000000000000
Wake : 0x0000000000000000 0x000000112dd7f24c 0x0000000000000000
panic(cpu 10 caller 0xffffff80003e2960): "Spinlock acquisition timed out: lock=0xffffff870fdd9e00, lock owner thread=0xffffff8705cb7d10, current_thread: 0xffffff8708bc8120, lock owner active on CPU 0x0, current owner: 0xffffff8705cb7d10, time: 4863941951392"@/AppleInternal/BuildRoot/Library/Caches/com.apple.xbs/Sources/xnu/xnu-7195.81.3/osfmk/i386/locks_i386.c:505
Backtrace (CPU 10), Frame : Return Address
0xffffffc18181bc30 : 0xffffff80002bab4d mach_kernel : _handle_debugger_trap + 0x3dd
0xffffffc18181bc80 : 0xffffff80003fd7e3 mach_kernel : _kdp_i386_trap + 0x143
0xffffffc18181bcc0 : 0xffffff80003ede1a mach_kernel : _kernel_trap + 0x55a
0xffffffc18181bd10 : 0xffffff800025fa2f mach_kernel : _return_from_trap + 0xff
0xffffffc18181bd30 : 0xffffff80002ba3ed mach_kernel : _DebuggerTrapWithState + 0xad
0xffffffc18181be50 : 0xffffff80002ba6d8 mach_kernel : _panic_trap_to_debugger + 0x268
0xffffffc18181bec0 : 0xffffff8000abef9a mach_kernel : _panic + 0x54
0xffffffc18181bf30 : 0xffffff80003e2960 mach_kernel : _spinlock_timeout_NMI
0xffffffc18181bf70 : 0xffffff80007f5ed6 mach_kernel : _workq_thread_set_max_qos + 0x1056
0xffffffc18181bfa0 : 0xffffff800025f13e mach_kernel : _call_continuation + 0x2e
Process name corresponding to current thread: com.apple.geod