I have read that some ASUS boards have a new bios with MSR unlocked, my problem has been that I changed the processor, I had a 7900x with an asus x299 prime de luxe v1 with bios 2002, everything worked perfect, I have a hd samsung 960 Pro 1TB with 3 different operating systems (High Sierra, Mojave and Catalina) but the same EFI, always starting perfectly with everyone. When changing to the i9 10900x the problems began, on the asus website it indicates that the Asus Prime deluxe v1 with bios 2002 accepts these processors, but in practice, in my case, it is not, I was talking to
@djlild7hina and he recommended the ssdt solution RTC0, AWAC, NOAWAC .. ufff none worked, so I opted for the patched bios version 3006, it worked in Mojave but in Catalina no, now I am with the bios 3105 version (web version) without patching, mojave starts a little more slow but the processor and graphics results are the highest, but in Catalina I cannot start, I have a mess ... I am attaching my EFI in case someone observes something strange, regards.
Edit: The serial numbers are deleted.