Just updated from 10.9.1 to 10.9.2 no Problems.
System :
[email protected] GTX 660TI
Gigabyte : ga-z87 hd3
Samsung 840D
I only have to reinstall the Audio drivers after every update.
I use both GPU. Intel with 22inch. Nvidia dual link 30inch screen and 27 full hd. No Problems.
Cheers tert