Thanks for your reply.
After some tweaking in BIOS thunderbolt settings, the Antelope Orion studio shows up in the Catalina, the launcher pops up, the mixer shows up, and I can find it inside sound hardwares list.
But, there is no sound, just like the early years. The AppleVTD is not working.
That's weird. I did exactly as the instruction said, enable VT-D, checked Config/plist, uninstalled the launcher and driver, installed the latest the driver, reset interface twice, and re-connect it, restart.....
Btw, I and using one Asus ThunderboltEX 3 add-in-card with original firmware. I do have a hot plug TB3 SSDT. I will boot up the computer with interface powered on and TB cable connected. And I found out that cold power on will activate the interface, if I restart the computer, the interface will not shows up.
Here are some snapshots